The skull tattoo is an emerging type of tattoo nowadays. While in the past older people chose skulls as body decoration, today rather the younger generation is eager to get a skull or skeleton tattoo.
Skulls have been involved in many religious activities, and in this way they can reflect religion as well as culture. In many religious countries, skulls are seen as a sign of victory, purity, or eternity (like in Mexico).
In some cultures though, skeletons have long been associated with death: the grim reaper depicts death itself that comes after everyone sooner or later; in Medieval times skeletons on stained glass windows were meant to remind people of their mortality.
Thus, it can be seen that skulls are highly ambiguous, and it depends on the culture whether it views it acceptable in tattoo form, or rather regrettable. One thing is for sure: if you have a skeleton tattoo you can expect remarks from people daily. If you are a kind that likes to make a stir, this tattoo is a good choice for you.
Some people love to decorate their bodies with skeletons, while some prefer tattoos that use one specific body part-mostly the skull. You can occasionally see skeletal hands, femur, or other minor body parts though. If you are looking for a big elaborate design, the full skeleton is preferable, but on smaller body parts probably a skull fits the most.
After all, the most important thing is your approach to skeletons: if you think they remind you of enjoying life, don't fear that others might think otherwise. Be proud of your personality, and then you can wear your tattoo with pride.